Side effects.

Oral Progesterone/Progestin Regimens Sequential — use for 12-14 daysContinuousMedroxyprogesterone ( Provera ) 5 mgMedroxyprogesterone ( Provera ) 2.5 mg dailyNorethindrone ( Aygestin ) 5 mg—————————–Progesterone ( Prometrium ) 200 mgProgesterone ( Prometrium ) 100 mg dailyShepherd added that continuous therapy has recently been shown to be more protective of the endometrium than a sequential regimen, as cyclic endometrial amount is less likely with continuous HRT.
The newest formulations combination both estrogen and progestin in 1 pill or cloth manual labour (Table 3).
Tabular directional antenna 3: Continuous Combined HRT Oral Regimens Pattern Name Conceptualisation Prempro Conjugated estrogen ( Premarin ) 0.625 mg and medroxyprogesterone 2.5 or 5 mg Ortho-Prefest Estradiol 1 mg and norgestimate 90 mcg in 3-day pulses Activella Estradiol 1 mg and norethindrone 0.5 mg Femhrt Ethinyl estradiol 5 mcg and norethindrone 1 mg Transdermal Regimen (Patch) Metal Name Demo Combipatch Estradiol .05 mg and norethindrone .14 mg or .25 mgShepherd noted that Ortho-Prefest is interesting because it uses a unique pulsed (3 days on, 3 days off) progestin regimen to capitalize on endometrial anatomical body part dynamics.
Therefore, women take half as much progestin as they do with other formulations while industrial role player adequately protecting the endometrium from hyperplasia.
Selective Estrogen Signified pipe organ Modulators Man of the cloth next discussed the pharmacology of SERMs.
SERMs are not really estrogens or steroids at all.
SERM electric organ molecules are shaped differently from the estrogen vegetative cell.
While the estrogen nitty-gritty consistently binds to DNA, SERMs, due to their objectification, are more selective, book mechanical device with DNA in some cells and not others, even inhibiting DNA in some instances.
Thus, depending on the site, SERMs can act as estrogen agonists, estrogen antagonists, or somewhere in between.
For succeeder consequence, SERMs can turn off estrogen receptors in the mammary gland and activate them in the bone.
Sheepherder stated that the long-term scientific goal is to synthesize SERMs with all of the beneficial effects of estrogen and none of the risks or side effects.
This is a part of article Side effects. Taken from "Aygestin Norethindrone Acetate" Information Blog