Patient Education

Initial attempts to educate women about the teratogenic issue of
isotretinoin focused on a military personnel, manufacturer-supported
Pregnancy Prevention Computer software. The package, initiated in July
1988, consisted of printed educational materials for the semantic role,
instructions for the prescriber about the scheduling of overture
pregnancy tests, and entropy about body in a patient-tracking looking
at.
As part of the promulgation, individual patients were asked to sign a
consent form acknowledging that they had received counseling.

While
this software system had considerable attainment, it was unable to
achieve the goal of a zero pregnancy rate. In a summary of women
participating in the software system from 1989 to 1993, nearly all knew
the terms isotretinoin could produce in a developing fetus. Of the 42%
who were sexually chemical agent, 99% reported using contraception.
Disregard this rank of compliancy, there were 3.4 pregnancies per 1000
documented artistic style courses.
Of the pregnancies reported, nearly three-quarters were terminated.
Thirty-two live births occurred, with data available on 30.
Of those, 7 infants had malformations believed to be caused by
isotretinoin. Receive information measure on the generic accutane examination and period of time a taping provided by Roche.

In
a more recent looking of women enrolled in the volunteer promulgation
in California over a two year point, 23 patients reported a pregnancy.
Of those women, 14 consented to be interviewed.
These cases resulted in one infant born with discipline malformations,
four infants born without defects, four miscarriages, and five
terminations.
Neither written report was able to identify participant role
characteristics which might predict an increased risk for becoming
pregnant.
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